Top 10 Joint Supplement that ACTUALLY WORK

Ingredient Description

Glucosamine Info
Glucosamine aids the body in repairing damaged or eroded cartilage, enhancing the body’s natural repair mechanisms, lessening joint pain and decreasing inflammation. The Centers for Disease Control and Prevention claims that one in two Americans is expected to get some form of osteoarthritis, the most common form of arthritis, in their lifetime, so glucosamine supplements are a fantastic addition to a healthy lifestyle. Regenasure glucosamine ensures that nearly everyone on a specialized diet can incorporate glucosamine supplements; Regenasure is the only commercially available vegetarian glucosamine. It is also shellfish-free and Kosher/Halal certified.

According to Richard Stenlake, a registered pharmacist who owns the largest compounding pharmacy in Australia, glucosamine is key for proper lubrication and nourishment of the body's cartilage. Without this lubrication and nourishment, the body's cartilage cracks and wears out, causing joint pain. He points out that glucosamine is a major building block of the water that helps the body's joints resist shocks (and thus resist cracking or wear). In 2006, the National Institutes of Health conducted a study on glucosamine called the Glucosamine/Chondroitin Arthritis Intervention Trial, or GAIT, which showed pain reduction in individuals with moderate or severe knee osteoarthritis. This offers evidence-based optimism toward glucosamine as a remedy for joint pain. It is important to note, however, that individuals within the study took chondroitin as well, another supplement that may help reduce joint pain and that is often mentioned alongside glucosamine.

Regenasure is a glucosamine supplement product that not only helps with joint health, but also has a number of unique attributes. Among these is its shellfish-free formulation, which has two main benefits. The first is that it is produced without the contaminants, environmental impact and seasonality related to the production and sourcing of shellfish-derived glucosamine. The second is that it is vegetarian-friendly; in fact, it is the only vegetarian glucosamine commercially available. Another unique attribute of Regenasure is its Kosher and Halal certifications, allowing individuals with these diet restrictions to access the joint health provided by glucosamine.

Glucosamine is considered safe and has promising clinical study results. With consistent ingestion of glucosamine supplements, possibly with the addition of chondroitin supplements, individuals can expect less joint pain and inflammation. Joints can benefit from the additional lubrication and nutritional benefits of glucosamine supplement products like Regenasure. Regenasure is an excellent glucosamine supplement product due, in part, to its shellfish-free property. As a shellfish-free product, Regenasure is not just vegetarian-friendly but is also produced without the contaminants, environmental impact and seasonality related to the production and sourcing of shellfish-derived glucosamine.

Chondroitin Info
Chondroitin sulfate is a drug derived from cow and pig cartilage. It is administered in 800 to 1,200 mg doses, once a day. It is used to treat osteoarthritis, in combination with other medical supplements. It is also effective in treating inflammation, heart disease, osteoporosis and high cholesterol. When combined with iron, it also increases mineral absorption and fights anemia.

Chondroitin sulfate was first produced as a medical grade supplement in the 1960s. It is extracted from the trachea, ear and nose of livestock and purified for use. It is commonly paired with glucosamine to stop the degenerative process of major cartilage and bone diseases.

Chondroitin sulfate works by providing the body with the building blocks needed to repair damaged tissue. Taking chondroitin sulfate gives the body the material needed to fill in gaps as the cartilage in and around joints begins to break down, slowing the rate of deterioration significantly. Those who took chondroitin sulfate to treat osteoarthritis not only reported that the deterioration of their joints had slowed, but also that they were experiencing less pain. Those that took chondroitin sulfate along with aspirin or ibuprofen had less visible swelling than those that did not.

Hylauronic Acid Info
Hylauronic acid is a great solution to joint problems and has several applications to joint health and well-being. Available in supplement form, the benefits of Hyaluronic acid, also known as Hyaluronan, if added to one's daily life, can promote healthy joints by enhancing the lubricating effects of the joint fluid.

Hyaluronic acid is a necessary protector of articular cartilage because it coats each cell of cartilage. When chemical bonds occur between hyaluronic acid and aggrecan monomers in the presence of link protein, the result is a greater resilience in the area cartilage. These chemical bonds, when formed, help slow the breakdown of cartilage by increasing the cartilage's resistance to compression.

Hyaluronic acid is a moderator of inflammation. It plays an important role during wound repair as an inducer of mild inflammation but also keeps inflammation in check. While this is a contradiction, this is actually the case. From the origination of tissue repair, hylauronic acid plays referee between the high rate of cell turnover during the initial repair and the stabilization of the tissue by tempering inflammatory cells as repair progresses.

Hylauronic acid is also a great tool for treating osteoarthritis on the knee joints. The treatment is fairly straightforward as the procedure simply involves direct injection to the location over the course of several applications. Hylauronic injections are typically a last resort before joint surgery because of the invasive nature of a surgical solution when compared to a simple injection. Hylauronic acid is known to enhance the viscosity of joint fluid which produces a lubricating, cushioning effect according to Adis International Limited. The acid is known to produce an analgesic effect as well.

Hyaluronan produces great results with slight inflammatory effects. The effects of the inflammation has no negative effect on the results of the healing process. Given the variety of treatments that are available for joint health, hyaluronan is a great addition to supplement health because it is naturally present in the body and serves the same purpose as the supplements.

Hyaluronan is a fantastic supplement for joint health because it is already present and working in the body. Given the wide variety of applications found naturally in the body the use of hyaluronan is a natural addition to target specific treatment. The need for invasive surgery is avoidable in some cases because of hyaluronan's rejuvenating effects on joint cartilage and fluid. Hyaluronan is positive proof that the body produces what it needs.

Anti-Inflammatory ingredients (grape seed, pycnogenol, boswelia resin extract, white willow bark extract, ginger root extract, alpha lipoic acid).

Anti-Inflammatory ingredients Info
As people get older, they often experience pain in their joints due to arthritis. Arthritis is caused by an erosion of cartilage between joints. Cartilage acts as a natural buffer between bones, and it regenerates itself during one's life. As people age, this regeneration slows. The resultant erosion of cartilage allows the bones at the joints to rub against one another, and this rubbing causes great pain for the sufferer. There are many natural ways one can both increase the health of joints and relieve the pain of arthritis. For instance, alpha lipoic acid is produced inside the body and attacks free radicals, and its production is boosted with simple changes to the diet like adding brewer's yeast. Many nutritional supplements have anti-inflammatory ingredients that help reduce the swelling of affected joints, including white willow bark extract, ginger root extract, grape seed, pycnogenol and boswelia resin extract.

Many people use white willow bark extract to reduce inflammation and pain and promote joint health. The beneficial ingredient in this extract is salicin, which is chemically very similar to the effective ingredient in aspirin. Several recent studies from the American Journal of Health show that this agent in white willow bark extract is effective in treating back pain as well as arthritis. Many users of this extract find that the pain-relieving effects of white willow bark extract are long-lasting.

Ginger root extract also has healing properties that are very effective for treating joint pain and maintaining joint health. The extract both reduces inflammation and decreases pain in the joints. Ginger root extract is readily available and easy to use, making it a wonderful supplement for those who suffer from joint pain.

Nutrient-rich grape seed is is an excellent source of anti-oxidants that also boasts anti-inflammatory properties. In addition to reducing the swelling that causes joints to ache, grape seed inhibits the degeneration of connective tissue like cartilage. Joint sufferers who include grape seed in their nutritional supplement regimen find relief from the pain of arthritis as well as a reduction in cartilage erosion.

Pycnogenol and boswelia resin extract, found in pine bark and resin respectively, are two more naturally-occurring substances that are useful for treating joint pain. Both of these supplements have properties that reduce swelling, and they also provide positive benefits to waning cartilage.

Pain in the joints is a natural part of the aging process. However, there are many supplements widely available that can offer relief through their anti-inflammatory properties. Some supplements, such as grape seed and pycnogenol, may also slow the degeneration of cartilage that causes joint pain. Before adding any natural supplements to one's diet, it is always advisable to speak to a physician. Many people find relief from their joint pain with nutritional supplements that are safe, natural and readily available.

Tumeric rhizome

Tumeric rhizome Info
Turmeric rhizome can assist in the alleviation of terrible joint pain. Asian cultures have long known that the healing and anti-oxidant properties of this magical herb are nothing short of miraculous. Those interested in Turmeric rhizome should learn more to determine if it is right for them.

Some are likely to know it as plain, old turmeric powder, and it sits in a little container on the spice rack. It lends a delightful, light Asian flavor to dishes and a beautiful golden hue to otherwise bland vegetables such as cauliflower. However, most probably do not know that turmeric rhizome is commonly used as an anti-oxidant, an anti-carcinogenic and an anti-inflammatory. Ancient Asian and Chinese cultures have used this herb, more commonly known as Saffron, for its miraculous properties for hundreds, even thousands of years.

As a supplement for maintaining joint health, anyone can ingest turmeric in a capsule form, consume it infused into a liquid or apply it topically when it is mixed into a paste. In certain studies, turmeric was shown just as effective, if not more, than the more popularly known Motrin, hydrocortisone or aspirin in the treatment and relief of joint pain. Another amazing benefit of using the herb is the lack of toxic side effects associated with other OTC drugs used for this purpose, such as kidney and liver problems.

The traditional school of thought is that curcumin is the effective compound of turmeric in the most commonly recognized powdered form. Curcumin is a deep orange or yellow color. There is also a concentrated version that is widely used, and that is the oil tincture. Although it is highly effective in the oil form, it retains most of its potency and effectiveness when in the powdered form.

The body naturally produces NF-kappa-b, which is a major cellular inflammatory agent, which induces the swelling and inflammation in the joints of the body. According to the Journal of Neuroscience, turmeric was proven to actually reduce the body's production of NF-kappa. In lab studies, the kappa cells were almost eliminated completely in mice.

Regardless of the underlying cause of the joint inflammation, sports injury, side effects of an accident or just tender, sore joints -- one should try turmeric. It is an inexpensive, safe to use, 100 percent natural and effective option to standard, organ-damaging medications usually purchased at the pharmacy. Anyone can conduct their own research and see for themselves.

Scutellaria baicalensis root and Acacia catechu heartwood

Scutellaria baicalensis root and Acacia catechu heartwood
For those suffering from joint health, the right nutritional supplement can seem like a miracle. There are several natural options for an effective treatment. Taken daily, the right supplement can alleviate pain, inflammation and give the user a higher level of mobility.

It is known that in joints, pain and tissue damage is generated by the body's conversion of arachidonic acid to other compounds. These other compounds are primarily cyclooxygenases-1 and 2 (COX-1 and 2) in addition to lipoxygenase-5 (LO-5). These compounds are the culprits responsible for causing inflammation of the joints, limiting movement, increasing pain and preventing a proper healing response. Several natural supplements are known to suppress these compounds, specifically Scutellaria baicalensis root and Acacia catechu heartwood.

Scutellaria baicalensis root, commonly known as Baikal Scullcap, has existed as a major component of traditional medicine for centuries. The species grows throughout Asia and is one of the primary ingredients in traditional Chinese medicine. The western world is just starting to learn of the plant's potential benefits. Currently, there are several studies that are attempting to gauge the effects of Baikal Scullcap on human health. Extracts of the plant are safe for consumption, but the level of anti-inflammatory effects and increases in joint health are still under debate. It is thought that the plant's phenolic compounds block the activity of COX-1 and 2 compounds, essentially stopping the inflammation reaction in damaged joints.

Another possible option for increasing joint health is Acacia catechu heartwood. There are several species of the Acacia plant, and they are found naturally in Africa and throughout Asia. Ongoing studies from the National Institute of Arthritis and Musculoskeletal and Skin Diseases have shown promise for the plant. Like Scutellaria baicalensis, Acacia species have the ability to inhibit COX-1 and 2 compounds, but might also have the ability to inhibit LO-5, a compound that remains unaffected by the traditionally used class of non-steroidal anti-inflammatory drugs (NSAIDs).

Several joint health supplements use blends of one or both of these possibly anti-inflammatory plants. One important blend of the two ingredients is Univestin, a proprietary ingredient that is now popular in many supplements aiming to reduce joint pain and inflammation. Several human trials have now demonstrated that Univestin is more effective than a placebo and improved the physical function of most patients.

The compound Univestin combines the anti-inflammatory of both Acacia catechu heartwood and Scutellaria baicalensis. It is found in many popular joint health supplements on the market and has some evidence backing its healing effects. Choosing the right supplement can help those suffering from joint issues regain mobility and quality of life, while experiencing little to none of the side-effects that come with the use of many prescription drugs.


Niacin Info
While many people are familiar with the use of niacin supplements to lower cholesterol levels, few are aware that the vitamin also has favorable effects on joint health. Niacin, also known as nicotinic acid or vitamin B-3, is a water-soluble substance that plans an active role in the health of the circulatory, adrenal and nervous systems. It is present in a number of foods, including liver, beets, fish and peanuts, but many people choose to supplement their dietary intake with over-the-counter supplements.

Despite its popularity as a means to lower HDL and LDL levels, nicotinic acid has promise as a joint supplement for patients with arthritis. Many rheumatologists recommend modest increases in niacin intake as a small step toward improved joint health. In 1996, W.B. Jonas conducted an extensive medical study on the potential benefits of niacin on arthritis pain and joint condition. His findings, which were later published in "Inflammation Research", reported a significant improvement in the overall joint flexibility and levels of inflammation in osteoarthritis patients following a 12-week regimen of niacinamide, another B-vitamin which is closely related to niacin.

Only a healthcare professional is qualified to determine the optimum dosage of niacin supplements, but the majority of individuals who use niacin for joint health adhere to a dosing regimen of 3,000 milligrams. The most common tablet size is approximately 500 milligrams, so doctors often suggest taking six 500-milligram tablets across the entire day as opposed to all at once. For many people, this reduces the flushing effect that is commonly linked to niacin use.

As with any supplement, niacin does have the potential to cause side effects. Fortunately, the side effects associated with a standard supplemental intake are minor and very few people stopped taking the supplements as a result of unwanted side effects. The most common side effect reported is noticeable flushing in the neck and face area, followed by a warming sensation in the face. Healthcare professionals note, however, that this effect tends to gradually subside within one to two weeks of continued usage.

While niacin supplements are most commonly taken to lower cholesterol levels, many healthcare professionals agree that the vitamin may also have beneficial effects on joint health in arthritis sufferers. Before taking over-the-counter niacin supplements, it is best to discuss the proper dosing regimen with a licensed nurse or doctor. This can greatly decrease the risk of potentially harmful interactions between niacin and prescription medications.


MSM Info
MSM, methylsulfonylmethane (METH-əl-sul-FON-il-METH-ane) provides sulfur, a vital building block of joints, cartilage, skin, hair and nails, and methyl groups, which support many vital biochemical processes in the body, including energy production. MSM is a naturally-occurring nutrient found in small amounts of many foods. As a dietary supplement, MSM is synthesized. When made correctly, it is identical to that found in nature. MSM can be taken alone or in combination with other joint health supplements, such as glucosamine and chondroitin.

MSM is thought to deliver sulfur to the body in a useable way. Sulfur helps maintain the structure of connective tissue by forming cross-linkages through disulfide bonds, i.e., sulfur strengthens the tissues that make up the joint.


Cissus Info
The ingredient Cissus Quadrangularis has been used safely in India for centuries. Some of the amazing properties of Cissus Quadrangularis are actual re-growth of tendons, ligaments and bone. Cissus can even help repair old, nagging injuries that have bothered you for years. As a rich source of carotenoids, triterpenoids and ascorbic acid it has potential for medical effects.

Medical researchers theorize that the use of Cissus quadrangularis increases the body's collagen turnover rate. Collagen, a fibrous protein that makes up about 25% of your body, connects the many cells and tissues of your body together, including bone, muscle, tendons, and ligaments.


SAMe Info
SAMe has been available as a dietary supplement in the US since 1999, but it has been used as a prescription drug in Italy since 1979, in Spain since 1985, and in Germany since 1989. Researchers discovered the potential usefulness of SAMe for treating osteoarthritis by accident. They were studying SAMe's effect on depression when the patients they were following reported an unexpected improvement in their osteoarthritis symptoms.

Using SAMe could help support your joints while improving your mood.